MOTS-c is one of the first characterised mitochondrial-derived peptides — a 16-residue reference in cellular energy-metabolism research. Full Kiwi Peps profile inside.
The MOTS-c peptide is a 16-residue peptide encoded within the mitochondrial 12S rRNA region and one of the first characterised mitochondrial-derived peptides (MDPs). Published in-vitro literature reports AMPK-pathway activation, GLUT4 translocation and glucose-metabolism endpoints in skeletal-muscle cell culture. MOTS-c sits alongside SS-31 and NAD+ precursors as a core reference in cellular energy-metabolism research panels.
MOTS-c peptide at a glance
| Attribute | Specification |
|---|---|
| Sequence | MRWQEMGYIFYPRKLR |
| Length | 16 residues |
| Origin | Encoded in mitochondrial 12S rRNA |
| Primary in-vitro endpoint | AMPK-pathway activation, GLUT4 translocation |
| Documented purity spec | ≥ 98% HPLC |
- Batch identifier and synthesis date traceable to the lot record
- HPLC purity ≥98% (typically ≥99% for peptides under 30 residues)
- LC-MS confirmed monoisotopic or average mass within ±0.5 Da of theoretical
- Counterion identity and content (acetate or trifluoroacetate) reported
- Bacterial endotoxin and residual solvents per the analytical method
MOTS-c peptide FAQ
What is the MOTS-c peptide?
MOTS-c is a 16-residue mitochondrial-derived peptide encoded within the 12S rRNA region, cited in published research for AMPK-pathway activation and glucose-metabolism endpoints in cell culture.
How does MOTS-c relate to SS-31?
Both are mitochondrial-research reference peptides. MOTS-c acts through AMPK signalling; SS-31 acts by binding cardiolipin at the inner mitochondrial membrane.
Where can New Zealand researchers buy MOTS-c?
Kiwi Peps supplies MOTS-c at ≥98% HPLC purity with third-party COA and same-day domestic dispatch. Research use only.
